Cholinergic Mechanisms in the Cerebral Cortex

Drug effect on cholinergic mechanisms in the cerebral cortex.

Investigations aimed to define the components of the cholinergic network in the cerebral cortex and their functional modifications under the effect of a number of psychotropic drugs are described. By measuring acetylcholine levels and acetylcholine output from the cerebral cortex in cats and rats with various subcortical lesions, at least two systems of cholinergic neurons ascending to the cort...

Molecular mechanisms regulating neurogenesis in the developing mouse cerebral cortex

Vision and movement mechanisms in the cerebral cortex.

ACKNOWLEDGEMENTS The HFSP Workshops were initiated by Michel Cuénod (Secretary-General, HFSPO) with the support of the Board of Trustees and the Council of Scientists. Lacquaniti (Rome) with the help of the HFSP staff. Our thanks go to the five co-editors who wrote the reports of the talks given at the meeting: These reports were edited into the present volume by Jennifer Altman (London). We th...

Cholinergic control of blood flow in the cerebral cortex of the rat.

Cholinergic Control of Blood Flow in the Cerebral Cortex of the Rat • Local blood flow was measured in the somatosensory cortex of urethanized rats by means of the hydrogen clearance method. The variations of cortical blood flow in the course of the anesthesia and the effects of the topical application of atropine, eserine and cholinomimetic drugs were studied. During urethan anesthesia, the el...

Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain.

OBJECTIVE Measures of cholinergic transmitter activity were investigated in patients with autism because of reported neuropathological abnormalities in cholinergic nuclei in the basal forebrain. METHOD Levels of cholinergic enzyme and receptor activity were measured in the frontal and parietal cerebral cortex of deceased autistic adults, similarly aged normal adults without mental retardation...